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Patricia Johansson Selected Research

T-Cell Prolymphocytic Leukemia (Leukemia, T Cell, Chronic)

1/2022T-cell prolymphocytic leukemia is associated with deregulation of oncogenic microRNAs on transcriptional and epigenetic level.
12/2020Mutations in PIGA cause a CD52-/GPI-anchor-deficient phenotype complicating alemtuzumab treatment in T-cell prolymphocytic leukemia.
1/2020Reconstruction of rearranged T-cell receptor loci by whole genome and transcriptome sequencing gives insights into the initial steps of T-cell prolymphocytic leukemia.
1/2020Anti-leukemic effect of CDK9 inhibition in T-cell prolymphocytic leukemia.

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Patricia Johansson Research Topics

Disease

4T-Cell Prolymphocytic Leukemia (Leukemia, T Cell, Chronic)
01/2022 - 01/2020
2Neoplasms (Cancer)
01/2022 - 01/2020
1Multiple Myeloma
04/2022
1Paroxysmal Hemoglobinuria (Paroxysmal Nocturnal Hemoglobinuria)
12/2020
1B-Cell Lymphoma (Lymphoma, B Cell)
01/2018
1Cryoglobulinemia
01/2018
1Wounds and Injuries (Trauma)
01/2013
1Carcinogenesis
01/2013
1B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
01/2013
1Disease Progression
01/2013

Drug/Important Bio-Agent (IBA)

2Proteins (Proteins, Gene)FDA Link
01/2020 - 01/2013
1venetoclaxIBA
04/2022
1Kv1.3 Potassium ChannelIBA
04/2022
1MicroRNAs (MicroRNA)IBA
01/2022
1Alemtuzumab (Campath)FDA Link
12/2020
1T-Cell Antigen Receptors (T-Cell Receptor)IBA
01/2020
1Immunoglobulin M (IgM)IBA
01/2018
1GranulinsIBA
01/2013
1ProgranulinsIBA
01/2013

Therapy/Procedure

1Therapeutics
04/2022
1Hematopoietic Stem Cell Transplantation
12/2020
1Drug Therapy (Chemotherapy)
01/2020